• "Randomized Clinical Trial Comparing a Thermosensitive Polymer (LeGoo) With Conventional Vessel Loops for Temporary Coronary Artery Occlusion During Off-Pump Coronary Artery Bypass Surgery." Gerhard Wimmer-Greinecker, MD, Olivier Bouchot, MD, Jean P. Verhoye, MD, Louis P. Perrault, MD, Jochen Börgermann, MD, Anno Diegeler, MD, Leen Van Garsse, MD, and Ardawan J. Rastan, MD. Ann Thorac Surg 2011;92:2177– 83
  Click title to view article
  
  
• "Clampless anastomosis with an intraluminal thermosensitive gel: First application in reconstructive microsurgery and literature review." G.A. Giessler, G.T. Fischborn, A.B. Schmidt. doi:10.1016/ j.bjps.2011.07.022
  Click title to view article
  
  
• "The Use of Reverse Thermosensitive Polymer (LeGoo) for Temporary Vessel Occlusion in Clampless Peripheral Vascular Surgery." Shalhoub J, Thapar A, Davies AH. Vasc Endovascular Surg. 2011 Jul;45(5):422-5
  Click title to view article
  
  
• "Clinical Experience with a Novel Thermosensitive Temporary Coronary Artery Occluder (LeGoo)." Olivier Bouchot, MD, Robert L. Berger, MD, Jean Pierre Berne, MD, François Brunotte, MD, and Roger Brenot, MD. Annals of Thoracic Surgery 2010;89:1912–7.
  Click title to view article
  
  
• "Facilitated anastomosis using a reverse thermo-sensitive polymer for temporary coronary occlusion in off-pump minimally invasive direct coronary artery bypass surgery." Ardawan Julian Rastan, Thilo Noack, Sreekumar Subramanian, Alpen Nacar, David Holzhey, Volkmar Falk and Friedrich Wilhelm Mohr. Interact CardioVasc Thorac Surg 2010;11:532-536
  Click title to view article
  
  
• "Thermosensitive Polymer Use for Shunt Sealing in Off-Pump Coronary Artery Bypass." Marco Agostini, MD, Francesco Lemut, MD, Vincenzo Di Gregorio, MD, and Claudio Grossi, MD. Innovations, Vol 5, Num 2, March/April 2010.
  Click title to view article
  
  
  

Selected pre-clinical peer reviewed publications.

• “Effects of purified poloxamer 407 gel on vascular occlusion and the coronary endothelium.” Munir Boodhwani, Jun Feng, Shigetoshi Mieno, Basel Ramlawi, Neel Sodha, Richard Clements, Frank W. Sellke. European Journal of Cardio-thoracic Surgery 29 (2006) 736-741.
  Click title to view article
  
  
•  “Safety and Efficacy of a Novel Gel for Vascular Occlusion in Off-Pump Surgery.” M Boodwhani, MD, W E Cohn, MD, J Feng, MD, PhD, B Ramlavi, MD, S Mieno, MD, A Schwarz, PhD, F W Sellke, MD, Ann Thorac Surg 2005; 80: 2333-7
  Click title to view article
  
  
•  “Temporary vascular occlusion with poloxamer 407.” J Raymond, A Metcalfe, I Salazkin, A Schwarz. Biomaterials 25 (2004) 3983
  Click title to view article
  
  
• “Hemostatic Control of Coronary Arteries With Poloxamer 407 Reverse-Thermal Polymer During Off-Pump Coronary Artery Bypass Surgery in a Pig Model.” William E. Cohn, Egemen Tuzun, Ryan Simonak, and Fred Baimbridge. Innovations 2007;2:36-39
  Click title to view article